olanzapine
Ligand Summary
The mechanism of action of olanzapine, as with other drugs having efficacy in schizophrenia, is unknown. However, it has been proposed that this drug’s efficacy in schizophrenia is mediated through a combination of dopamine and serotonin type 2 (5HT2) antagonism. The mechanism of action of olanzapine in the treatment of acute manic or mixed episodes associated with bipolar I disorder is unknown.
UNII: N7U69T4SZR
PubChem: 135398745
PubChem: 4585
Guide to Pharmacology: 47
ChEMBL: CHEMBL715
DrugCentral: 1982
LyCHI: TKL1QMDDLD87
Target Activities
177 Activities
Items per page:
10
1 – 10 of 177
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
- | ||||||
- | ||||||
Ki | ||||||
Ki | ||||||