nitroprusside
Ligand Summary
Sodium nitroprusside interacts with oxyhemoglobin to produce methemoglobin, cyanide, and nitric oxide (NO). NO then reacts with guanylate cyclase in vascular smooth muscle to produce cGMP that reduces intracellular calcium concentrations resulting in relaxation of vascular smooth muscle and consequent dilatation of peripheral arteries and veins.
ChEMBL: CHEMBL2097081
DrugCentral: 4631
LyCHI: nitroprusside
Target Activities
4 Activities
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1 – 4 of 4
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