niflumic acid
An analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
Ligand Summary
UNII: 4U5MP5IUD8
PubChem: 4488
Guide to Pharmacology: 2439
ChEMBL: CHEMBL63323
DrugCentral: 1925
LyCHI: 4VJD167PTD4T
Target Activities
KCNT2
Potassium channel subfamily T member 2
2 Activities
Items per page:
1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 8.68 | |||||
EC50 | 8.68 | ACTIVATOR | ||||
TTR
Transthyretin
2 Activities
Items per page:
1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 6.58 | J. Med. Chem., (2015) 58:16:6507 | ||||
IC50 | 6.54 | None, (2014) None:None:None | ||||
TRPA1
Transient receptor potential cation channel subfamily A member 1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
- | 3.3 | |||||
PTGS2
Prostaglandin G/H synthase 2
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.04 | None, None:None:None | ||||
CLCNKB
Chloride channel protein ClC-Kb
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 5 | ACTIVATOR | ||||
CLCNKA
Chloride channel protein ClC-Ka
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 5 | ACTIVATOR | ||||