mecamylamine
Ligand Summary
A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
UNII: 5Y1141YI4U
PubChem: 4032
Guide to Pharmacology: 3990
ChEMBL: CHEMBL267936
DrugCentral: 1646
LyCHI: 1KLYDCDX2PT4
Target Activities
9 Activities
Items per page:
10
1 – 9 of 9
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | ||||||
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Ki | NEGATIVE ALLOSTERIC MODULATOR | |||||
Ki | NEGATIVE ALLOSTERIC MODULATOR | |||||
IC50 | ||||||