lumacaftor
Ligand Summary
Lumacaftor improves the conformational stability of F508del-CFTR, resulting in increased processing and trafficking of mature protein to the cell surface.
UNII: EGP8L81APK
PubChem: 16678941
ChEMBL: CHEMBL2103870
DrugCentral: 5010
LyCHI: D77H12SA6VK3
Target Activities
5 Activities
Items per page:
10
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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EC50 | PHARMACOLOGICAL CHAPERONE | |||||