lisinopril
One of the ANGIOTENSIN-CONVERTING ENZYME INHIBITORS (ACE inhibitors), orally active, that has been used in the treatment of hypertension and congestive heart failure.
Ligand Summary
UNII: 7Q3P4BS2FD
PubChem: 5362118
PubChem: 5362119
PubChem: 139146300
Guide to Pharmacology: 6360
ChEMBL: CHEMBL419213
ChEMBL: CHEMBL1237
DrugCentral: 1587
LyCHI: 6Y1P65W348W7
Target Activities
ACE
Angiotensin-converting enzyme
12 Activities
Items per page:
1 – 10 of 12
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 9.4 | |||||
IC50 | 10 | J. Med. Chem., (2003) 46:15:3326 | ||||
IC50 | 10 | Bioorg. Med. Chem., (2013) 21:22:7216 | ||||
IC50 | 8.92 | J. Med. Chem., (1993) 36:16:2390 | ||||
IC50 | 8.92 | J. Med. Chem., (1993) 36:15:2051 | ||||
IC50 | 8.92 | J. Med. Chem., (2002) 45:26:5609 | ||||
IC50 | 8.33 | J. Med. Chem., (2000) 43:3:305 | ||||
IC50 | 8.1 | Eur J Med Chem, (2017) 141:None:417 | ||||
Ki | 7.29 | Bioorg. Med. Chem. Lett., (2006) 16:17:4616 | ||||
Ki | 6.88 | Bioorg. Med. Chem. Lett., (2006) 16:17:4616 | ||||