linoleic acid
Ligand Summary
A doubly unsaturated fatty acid, occurring widely in plant glycosides. It is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes. (From Stedman, 26th ed)
UNII: 9KJL21T0QJ
PubChem: 5280450
PubChem: 23684895
Guide to Pharmacology: 1052
ChEMBL: CHEMBL267476
ChEMBL: CHEMBL3122088
DrugCentral: 3323
LyCHI: 441TNZQ7HKW4
Target Activities
FABP3
Fatty acid-binding protein, heart
5 Activities
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1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 9.7 | Bioorg. Med. Chem., (2014) 22:6:1804 | ||||
IC50 | 6 | Bioorg. Med. Chem. Lett., (2010) 20:12:3675 | ||||
IC50 | 6 | Eur. J. Med. Chem., (2015) 90:None:241 | ||||
IC50 | 6 | Eur. J. Med. Chem., (2015) 90:None:241 | ||||
Kd | 9.7 | |||||
KCNB1
Potassium voltage-gated channel subfamily B member 1
2 Activities
FABP4
Fatty acid-binding protein, adipocyte
2 Activities
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1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6 | Bioorg. Med. Chem. Lett., (2010) 20:12:3675 | ||||
IC50 | 6 | |||||
FFAR4
Free fatty acid receptor 4
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 5.89 | |||||
PPARG
Peroxisome proliferator-activated receptor gamma
1 Activities
PPARA
Peroxisome proliferator-activated receptor alpha
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.32 | Med Chem Res, (2009) 18:1:8 | ||||