levorphanol
A narcotic analgesic that may be habit-forming. It is nearly as effective orally as by injection.
Ligand Summary
UNII: 27618J1N2X
PubChem: 21139913
PubChem: 5359272
PubChem: 53324694
Guide to Pharmacology: 7595
ChEMBL: CHEMBL2062261
ChEMBL: CHEMBL592
ChEMBL: CHEMBL1628243
DrugCentral: 1574
LyCHI: 1U43KCX12F39
Target Activities
OPRD1
Delta-type opioid receptor
11 Activities
Items per page:
1 – 10 of 11
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
IC50 | 8.54 | J. Med. Chem., (1989) 32:6:1259 | ||||
Ki | 8.38 | J. Med. Chem., (2004) 47:8:1886 | ||||
Ki | 8.38 | J. Med. Chem., (2003) 46:24:5162 | ||||
Ki | 8.38 | J. Med. Chem., (2004) 47:1:165 | ||||
Ki | 8.38 | J. Med. Chem., (2000) 43:1:114 | ||||
Ki | 8.38 | Bioorg. Med. Chem. Lett., (2001) 11:20:2735 | ||||
Ki | 8.38 | J. Med. Chem., (2006) 49:1:256 | ||||
Ki | 8.38 | Bioorg. Med. Chem. Lett., (2007) 17:6:1508 | ||||
Ki | 8.38 | Bioorg. Med. Chem. Lett., (2008) 18:16:4474 | ||||
Ki | 8.38 | J. Med. Chem., (2012) 55:8:3878 | ||||
OPRM1
Mu-type opioid receptor
9 Activities
Items per page:
1 – 9 of 9
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
IC50 | 9.89 | |||||
IC50 | 9.89 | J. Med. Chem., (2003) 46:1:34 | ||||
Ki | 9.68 | J. Med. Chem., (2004) 47:8:1886 | ||||
Ki | 9.68 | J. Med. Chem., (2003) 46:24:5162 | ||||
Ki | 9.68 | J. Med. Chem., (2006) 49:1:256 | ||||
Ki | 9.68 | Bioorg. Med. Chem. Lett., (2007) 17:6:1508 | ||||
Ki | 9.68 | Bioorg. Med. Chem. Lett., (2008) 18:16:4474 | ||||
Ki | 9.68 | J. Med. Chem., (2012) 55:8:3878 | ||||
Ki | 9.68 | AGONIST | ||||
OPRK1
Kappa-type opioid receptor
7 Activities
Items per page:
1 – 7 of 7
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
Ki | 8.64 | J. Med. Chem., (2003) 46:24:5162 | ||||
Ki | 8.64 | J. Med. Chem., (2004) 47:8:1886 | ||||
Ki | 8.64 | J. Med. Chem., (2006) 49:1:256 | ||||
Ki | 8.64 | Bioorg. Med. Chem. Lett., (2007) 17:6:1508 | ||||
Ki | 8.64 | Bioorg. Med. Chem. Lett., (2008) 18:16:4474 | ||||
Ki | 8.64 | J. Med. Chem., (2012) 55:8:3878 | ||||
IC50 | 8.4 | J. Med. Chem., (2003) 46:1:34 | ||||
GRIN2C
Glutamate receptor ionotropic, NMDA 2C
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
IC50 | 6.22 | |||||