Pharos : Ligand Details - laropiprant

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a potent orally active human prostaglandin D(2) receptor 1 antagonist

Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

PubChem: 9867642

ChEMBL: CHEMBL426559

DrugCentral: 4326

LyCHI: CWKU69N7GNF7

Target Activities

Explore Associated and Predicted Targets

PTGDR

Tclin

Prostaglandin D2 receptor

6 Activities

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1 – 6 of 6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	10.52		J. Med. Chem., (2007) 50:4:794	17300164

IC50	10.05		J. Med. Chem., (2007) 50:4:794	17300164

Ki	9.24		J. Med. Chem., (2007) 50:4:794	17300164

IC50	8.85		J. Med. Chem., (2007) 50:4:794	17300164

IC50	8.4		J. Med. Chem., (2007) 50:4:794	17300164

Kd	10.52	ANTAGONIST	http://www.ncbi.nlm.nih.gov/pubmed/17300164

TBXA2R

Tclin

Thromboxane A2 receptor

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.53		J. Med. Chem., (2007) 50:4:794	17300164

Kd	7.96		J. Med. Chem., (2007) 50:4:794	17300164