indapamide
A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
Ligand Summary
Target Activities
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10
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CA7
Carbonic anhydrase 7
4 Activities
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1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 6.52 | Bioorg. Med. Chem., (2010) 18:21:7357 | ||||
Kd | 6.52 | Bioorg. Med. Chem., (2013) 21:22:6937 | ||||
Ki | 9.64 | Bioorg. Med. Chem., (2009) 17:3:1214 | ||||
Ki | 9.64 | Eur. J. Med. Chem., (2014) 71:None:105 | ||||
CA13
Carbonic anhydrase 13
3 Activities
CA2
Carbonic anhydrase 2
3 Activities
CA9
Carbonic anhydrase 9
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.44 | Bioorg. Med. Chem., (2009) 17:3:1214 | ||||
CA5B
Carbonic anhydrase 5B, mitochondrial
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.56 | Bioorg. Med. Chem., (2009) 17:3:1214 | ||||
CA12
Carbonic anhydrase 12
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 8 | Bioorg. Med. Chem., (2009) 17:3:1214 | ||||
CA6
Carbonic anhydrase 6
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 6.6 | Bioorg. Med. Chem., (2013) 21:22:6937 | ||||
CA5A
Carbonic anhydrase 5A, mitochondrial
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.05 | Bioorg. Med. Chem., (2009) 17:3:1214 | ||||
CA4
Carbonic anhydrase 4
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.67 | Bioorg. Med. Chem., (2009) 17:3:1214 | ||||
SLC12A3
Solute carrier family 12 member 3
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
A2 | 7.54 | INHIBITOR | ||||