indapamide
A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
Ligand Summary
Target Activities
CA7
Carbonic anhydrase 7
6 Activities
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1 – 6 of 6
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 9.64 | Bioorg. Med. Chem., (2009) 17:3:1214 | ||||
Ki | 9.64 | Eur. J. Med. Chem., (2014) 71:None:105 | ||||
Kd | 8.84 | Bioorg Med Chem, (2018) 26:3:675 | ||||
Kd | 6.6 | Bioorg Med Chem, (2018) 26:3:675 | ||||
Kd | 6.52 | Bioorg. Med. Chem., (2010) 18:21:7357 | ||||
Kd | 6.52 | Bioorg. Med. Chem., (2013) 21:22:6937 | ||||
CA2
Carbonic anhydrase 2
5 Activities
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1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.42 | Bioorg Med Chem, (2018) 26:3:675 | ||||
Kd | 6.7 | Bioorg. Med. Chem., (2010) 18:21:7357 | ||||
Kd | 6.52 | Bioorg. Med. Chem., (2010) 18:21:7357 | ||||
Kd | 6.52 | Bioorg. Med. Chem., (2013) 21:22:6937 | ||||
Kd | 6.28 | Bioorg Med Chem, (2018) 26:3:675 | ||||
CA13
Carbonic anhydrase 13
5 Activities
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1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.39 | Bioorg Med Chem, (2018) 26:3:675 | ||||
Kd | 7 | Bioorg. Med. Chem., (2010) 18:21:7357 | ||||
Kd | 7 | Bioorg. Med. Chem., (2013) 21:22:6937 | ||||
Kd | 6.7 | Bioorg. Med. Chem., (2010) 18:21:7357 | ||||
Kd | 6.54 | Bioorg Med Chem, (2018) 26:3:675 | ||||
CA6
Carbonic anhydrase 6
3 Activities
CA9
Carbonic anhydrase 9
3 Activities
CA4
Carbonic anhydrase 4
3 Activities
CA5B
Carbonic anhydrase 5B, mitochondrial
3 Activities
CA5A
Carbonic anhydrase 5A, mitochondrial
3 Activities
CA12
Carbonic anhydrase 12
2 Activities
CA14
Carbonic anhydrase 14
2 Activities
CA1
Carbonic anhydrase 1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 6.58 | Bioorg Med Chem, (2018) 26:3:675 | ||||
CA3
Carbonic anhydrase 3
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 6.98 | Bioorg Med Chem, (2018) 26:3:675 | ||||
SLC12A3
Solute carrier family 12 member 3
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
A2 | 7.54 | INHIBITOR | ||||