hydroxycarbamide
Ligand Summary
An antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.
UNII: X6Q56QN5QC
PubChem: 3657
Guide to Pharmacology: 6822
ChEMBL: CHEMBL467
DrugCentral: 1399
LyCHI: YS9WPYDSAP5A
Target Activities
RRM1
Ribonucleoside-diphosphate reductase large subunit
2 Activities
Items per page:
1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 3.83 | |||||
INHIBITOR | ||||||
RRM2
Ribonucleoside-diphosphate reductase subunit M2
2 Activities
Items per page:
1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 3.83 | |||||
INHIBITOR | ||||||