halothane
A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178)
Ligand Summary
Target Activities
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KCNK3
Potassium channel subfamily K member 3
2 Activities
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EC50 | 3 | |||||
OPENER | ||||||
KCNK5
Potassium channel subfamily K member 5
1 Activities
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3.7 | ||||||
KCNB1
Potassium voltage-gated channel subfamily B member 1
1 Activities
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3.5 | ||||||
GLRA1
Glycine receptor subunit alpha-1
1 Activities
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POSITIVE MODULATOR | ||||||
GLRB
Glycine receptor subunit beta
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GABRP
Gamma-aminobutyric acid receptor subunit pi
1 Activities
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POSITIVE ALLOSTERIC MODULATOR | ||||||
GABRD
Gamma-aminobutyric acid receptor subunit delta
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POSITIVE ALLOSTERIC MODULATOR | ||||||
GABRA1
Gamma-aminobutyric acid receptor subunit alpha-1
1 Activities
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POSITIVE ALLOSTERIC MODULATOR | ||||||
GABRB1
Gamma-aminobutyric acid receptor subunit beta-1
1 Activities
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POSITIVE ALLOSTERIC MODULATOR | ||||||
GABRG2
Gamma-aminobutyric acid receptor subunit gamma-2
1 Activities
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POSITIVE ALLOSTERIC MODULATOR | ||||||