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fostamatinib

Ligand Summary
Ligand Structure
Rendered image for the query structure
Description
Fostamatinib is a tyrosine kinase inhibitor with demonstrated activity against spleen tyrosine kinase (SYK). The major metabolite of fostamatinib, R406, inhibits signal transduction of Fc-activating receptors and B-cell receptor. The fostamatinib metabolite R406 reduces antibody-mediated destruction of platelets.
Synonyms & Links
DrugCentral: 5280
LyCHI:  YYH232CPYC1D


Target Activities