fostamatinib
Ligand Summary
Fostamatinib is a tyrosine kinase inhibitor with demonstrated activity against spleen tyrosine kinase (SYK). The major metabolite of fostamatinib, R406, inhibits signal transduction of Fc-activating receptors and B-cell receptor. The fostamatinib metabolite R406 reduces antibody-mediated destruction of platelets.
UNII: SQ8A3S5101
PubChem: 11671467
PubChem: 146673142
ChEMBL: CHEMBL2103830
ChEMBL: CHEMBL3989516
DrugCentral: 5280
LyCHI: YYH232CPYC1D
Target Activities
36 Activities
Items per page:
10
1 – 10 of 36
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