fosdenopterin
Ligand Summary
Fosdenopterin provides an exogenous source of cPMP. cPMP is converted to molybdopterin, which is then converted to molybdenum cofactor (MoCo) and restores molybdenum cofactor biosynthesis. In MOCD Type A, mutations in MOCS1 lead to deficient MOCS1A/B-dependent synthesis of cPMP, which subsequently results in deficient molybdenum-dependent enzyme activity (e.g., sulfite oxidase).
UNII: 4X7K2681Y7
PubChem: 135463437
ChEMBL: CHEMBL2338675
DrugCentral: 5444
LyCHI: D67J1NMVCYFU
Target Activities
1 Activities
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