everolimus
Ligand Summary
A derivative of sirolimus and an inhibitor of TOR SERINE-THREONINE KINASES. It is used to prevent GRAFT REJECTION in heart and kidney transplant patients by blocking cell proliferation signals. It is also an ANTINEOPLASTIC AGENT.
UNII: 9HW64Q8G6G
PubChem: 6442177
Guide to Pharmacology: 5889
ChEMBL: CHEMBL1908360
DrugCentral: 1118
LyCHI: 3XY9KTG65JPM
Target Activities
4 Activities
Items per page:
10
1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | ||||||
Kd | ||||||
IC50 | ||||||
IC50 | INHIBITOR | |||||