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etoposide phosphate

Ligand Summary
Ligand Structure
Rendered image for the query structure
Etoposide phosphate is a prodrug that is converted to its active moiety, etoposide, by dephosphorylation. Etoposide causes the induction of DNA strand breaks by an interaction with DNA-topoisomerase II or the formation of free radicals, leading to cell cycle arrest, primarily at the G2 stage of the cell cycle, and cell death.
Synonyms & Links
DrugCentral: 3944