ertugliflozin
Ligand Summary
SGLT2 is the predominant transporter responsible for reabsorption of glucose from the glomerular filtrate back into the circulation. Ertugliflozin is an inhibitor of SGLT2. By inhibiting SGLT2, ertugliflozin reduces renal reabsorption of filtered glucose and lowers the renal threshold for glucose, and thereby increases urinary glucose excretion.
UNII: 6C282481IP
PubChem: 44814423
Guide to Pharmacology: 8376
ChEMBL: CHEMBL1770248
DrugCentral: 5270
LyCHI: NHG4URM73JQB
Target Activities
9 Activities
Items per page:
10
1 – 9 of 9
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