emapalumab
Ligand Summary
Emapalumab-lzsg is a monoclonal antibody that binds to and neutralizes interferon gamma (IFNgamma). Nonclinical data suggest that IFNgamma plays a pivotal role in the pathogenesis of HLH by being hypersecreted.
ChEMBL: CHEMBL3989977
DrugCentral: 5320
LyCHI: emapalumab
Target Activities
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Kd | ANTIBODY BINDING | |||||