eluxadoline
Ligand Summary
Eluxadoline is a mu-opioid receptor agonist; eluxadoline is also a delta opioid receptor antagonist and a kappa opioid receptor agonist. The binding affinities (Ki) of eluxadoline for the human mu and delta opioid receptors are 1.8 nM and 430 nM, respectively. The binding affinity (Ki) of eluxadoline for the human kappa opioid receptor has not been determined; however, the Ki for guinea pig cerebellum kappa opioid receptor is 55 nM. In animals, eluxadoline interacts with opioid receptors in the gut.
UNII: 45TPJ4MBQ1
PubChem: 130406582
PubChem: 11250029
Guide to Pharmacology: 7691
ChEMBL: CHEMBL2159122
DrugCentral: 5001
LyCHI: K7W3932HVKSB
Target Activities
6 Activities
Items per page:
1 – 6 of 6
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