dronedarone
Ligand Summary
Dronedarone has antiarrhythmic properties belonging to all four Vaughan-Williams classes, but the contribution of each of these activities to the clinical effect is unknown.
UNII: JQZ1L091Y2
PubChem: 208898
PubChem: 219025
Guide to Pharmacology: 7465
ChEMBL: CHEMBL184412
ChEMBL: CHEMBL1201729
DrugCentral: 4112
LyCHI: MFWXQ3S2LQB2
Target Activities
KCNA5
Potassium voltage-gated channel subfamily A member 5
2 Activities
KCNH2
Potassium voltage-gated channel subfamily H member 2
2 Activities
HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
BLOCKER | ||||||
HCN2
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
BLOCKER | ||||||
HCN3
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
BLOCKER | ||||||
HCN4
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
BLOCKER | ||||||