doxorubicin
Antineoplastic antibiotic obtained from Streptomyces peucetius. It is a hydroxy derivative of DAUNORUBICIN.
Ligand Summary
PubChem: 31703
PubChem: 657367
Guide to Pharmacology: 7069
ChEMBL: CHEMBL53463
ChEMBL: CHEMBL359744
DrugCentral: 960
LyCHI: FA7PVTGAWGXF
Target Activities
TOP2A
DNA topoisomerase 2-alpha
7 Activities
Items per page:
1 – 7 of 7
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6 | |||||
IC50 | 6.22 | J Med Chem, (2019) 62:6:2950 | ||||
IC50 | 6.06 | Eur J Med Chem, (2018) 155:None:117 | ||||
IC50 | 6.03 | Bioorg Med Chem Lett, (2020) 30:14:127246 | ||||
IC50 | 6 | J. Nat. Prod., (2001) 64:2:204 | ||||
IC50 | 6 | J. Nat. Prod., (2001) 64:2:204 | ||||
IC50 | 6 | INHIBITOR | ||||
S100A4
Protein S100-A4
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
AC50 | 6.49 | None, None:None:None | ||||