docetaxel
A semisynthetic analog of PACLITAXEL used in the treatment of locally advanced or metastatic BREAST NEOPLASMS and NON-SMALL CELL LUNG CANCER.
Ligand Summary
UNII: 699121PHCA
PubChem: 148123
ChEMBL: CHEMBL3545252
DrugCentral: 939
LyCHI: UHFR3MZHPXJJ
Target Activities
EGFR
Epidermal growth factor receptor
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 9.09 | Proc. Natl. Acad. Sci. U.S.A., (2007) 104:6:1943 | ||||
GHRHR
Growth hormone-releasing hormone receptor
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 9.85 | Proc. Natl. Acad. Sci. U.S.A., (2007) 104:6:1943 | ||||
TUBB
Tubulin beta chain
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
ID50 | 6.7 | INHIBITOR | ||||
TUBB1
Tubulin beta-1 chain
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
ID50 | 6.7 | INHIBITOR | ||||
TUBB2A
Tubulin beta-2A chain
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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ID50 | 6.7 | INHIBITOR | ||||
TUBB2B
Tubulin beta-2B chain
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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ID50 | 6.7 | INHIBITOR | ||||
TUBB3
Tubulin beta-3 chain
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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ID50 | 6.7 | INHIBITOR | ||||
TUBB4A
Tubulin beta-4A chain
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
ID50 | 6.7 | INHIBITOR | ||||
TUBB4B
Tubulin beta-4B chain
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
ID50 | 6.7 | INHIBITOR | ||||
TUBB6
Tubulin beta-6 chain
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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ID50 | 6.7 | INHIBITOR | ||||
TUBB8
Tubulin beta-8 chain
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
ID50 | 6.7 | INHIBITOR | ||||