ditiocarb
Ligand Summary
A chelating agent that has been used to mobilize toxic metals from the tissues of humans and experimental animals. It is the main metabolite of DISULFIRAM.
UNII: 99Z2744345
PubChem: 533728
PubChem: 8987
ChEMBL: CHEMBL107217
ChEMBL: CHEMBL961
DrugCentral: 931
LyCHI: RJUMF7YA7H38
Target Activities
CA1
Carbonic anhydrase 1
4 Activities
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1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.1 | Bioorg. Med. Chem. Lett., (2009) 19:7:1855 | ||||
Ki | 6.1 | Bioorg. Med. Chem., (2011) 19:1:243 | ||||
Ki | 6.1 | J. Med. Chem., (2012) 55:4:1721 | ||||
Ki | 6.1 | Bioorg. Med. Chem. Lett., (2014) 24:18:4389 | ||||
CYP2E1
Cytochrome P450 2E1
2 Activities
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1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.07 | None, (2015) None:None:None | ||||
IC50 | 6.07 | |||||
GSDMD
Gasdermin-D
2 Activities
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1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.4 | MedChemComm, (2019) 10:5:660 | ||||
IC50 | 6.4 | |||||