dinoprost
A naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due to its vasocontractile properties, the compound has a variety of other biological actions.
Ligand Summary
UNII: B7IN85G1HY
PubChem: 5280363
Guide to Pharmacology: 1884
ChEMBL: CHEMBL815
DrugCentral: 912
LyCHI: GCAJ7BC694FA
Target Activities
PTGFR
Prostaglandin F2-alpha receptor
8 Activities
Items per page:
1 – 8 of 8
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
8.5 | ||||||
IC50 | 8.6 | Bioorg. Med. Chem. Lett., (2000) 10:14:1519 | ||||
IC50 | 8.52 | J. Med. Chem., (2001) 44:24:4157 | ||||
IC50 | 8.15 | J. Med. Chem., (2000) 43:5:945 | ||||
EC50 | 7.61 | Bioorg. Med. Chem. Lett., (2004) 14:17:4525 | ||||
IC50 | 7.37 | J. Med. Chem., (1989) 32:1:256 | ||||
EC50 | 7.1 | Bioorg. Med. Chem. Lett., (2000) 10:14:1519 | ||||
Kd | 8.4 | AGONIST | ||||
PTGER3
Prostaglandin E2 receptor EP3 subtype
4 Activities
PTGDR2
Prostaglandin D2 receptor 2
2 Activities
PTGER1
Prostaglandin E2 receptor EP1 subtype
2 Activities
PTGER4
Prostaglandin E2 receptor EP4 subtype
2 Activities
PTGER2
Prostaglandin E2 receptor EP2 subtype
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
5.6 | ||||||
TBXA2R
Thromboxane A2 receptor
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
5.1 | ||||||
SLCO2A1
Solute carrier organic anion transporter family member 2A1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.64 | Am. J. Physiol., (1999) 277:1:R734 | ||||