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daprodustat

Ligand Summary
Ligand Structure
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Description
Daprodustat is a small molecule inhibitor of hypoxia-inducible factor prolyl hydroxylase (PHD) developed for the treatment of anaemia in patients with chronic kidney disease (CKD). Inhibition of PHD prevents degradation of hypoxia-inducible factor (HIF), leading to the production of erythropoietin and subsequent induction of erythropoiesis.
Synonyms & Links
DrugCentral: 5421
LyCHI:  CZATVQLWJ8Y1


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Target Activities