cyclothiazide
Ligand Summary
inhibits the desensitization of AMPA-type receptors; structure
UNII: P71U09G5BW
PubChem: 2910
Guide to Pharmacology: 4167
ChEMBL: CHEMBL61593
DrugCentral: 761
LyCHI: T7FVTQTA19HS
Target Activities
GRIA1
Glutamate receptor 1
4 Activities
Items per page:
1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 4.72 | |||||
EC50 | 6 | Bioorg. Med. Chem., (2010) 18:4:1381 | ||||
EC50 | 5.7 | Bioorg. Med. Chem., (2010) 18:4:1381 | ||||
EC50 | 5 | Bioorg. Med. Chem., (2010) 18:4:1381 | ||||
GRIA2
Glutamate receptor 2
3 Activities
GRIA4
Glutamate receptor 4
3 Activities
GRIA3
Glutamate receptor 3
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 4.86 | |||||
SLC12A3
Solute carrier family 12 member 3
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
INHIBITOR | ||||||