crizanlizumab
Ligand Summary
Crizanlizumab-tmca is a humanized IgG2 kappa monoclonal antibody that binds to P-selectin and blocks interactions with its ligands including P-selectin glycoprotein ligand 1. Binding P-selectin on the surface of the activated endothelium and platelets blocks interactions between endothelial cells, platelets, red blood cells, and leukocytes.
ChEMBL: CHEMBL4297734
DrugCentral: 5365
LyCHI: crizanlizumab
Target Activities
1 Activities
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