corifollitropin alfa
Ligand Summary
Corifollitropin alfa is designed as a sustained follicle stimulant with the same pharmacodynamic profile as (rec)FSH, but with a markedly prolonged duration of FSH activity. Due to its ability to initiate and sustain multiple follicular growth for an entire week, a single subcutaneous injection of the recommended dose of Corifollitropin alfa may replace the first seven injections of any daily (rec)FSH preparation in a COS treatment cycle. The long duration of FSH activity was achieved by adding the carboxy-terminal peptide of the beta-subunit of human chorionic gonadotropin (hCG) to the beta-chain of human FSH. Corifollitropin alfa does not display any intrinsic LH/hCG activity.
ChEMBL: CHEMBL2108185
DrugCentral: 5245
LyCHI: corifollitropin alfa
Target Activities
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