Pharos : Ligand Details - chidamide

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: Chidamide

PubChem: 9800555

ChEMBL: CHEMBL4087968

LyCHI: GDXL2PSBTW5R

Target Activities

Explore Associated and Predicted Targets

HDAC1

Tclin

Histone deacetylase 1

6 Activities

Items per page:

1 – 6 of 6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.02		Eur J Med Chem, (2019) 183:None:111691	31536895

IC50	6.8		Bioorg Med Chem Lett, (2020) 30:8:127036	32088129

IC50	6.72		Eur J Med Chem, (2019) 173:None:185	31003060

IC50	6.72		Eur J Med Chem, (2019) 176:None:195	31103900

IC50	6.27		Eur J Med Chem, (2018) 143:None:320	29202397

IC50	6.06		Bioorg Med Chem Lett, (2017) 27:14:3162	28532668

HDAC2

Tclin

Histone deacetylase 2

4 Activities

Items per page:

1 – 4 of 4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.8		Eur J Med Chem, (2019) 183:None:111691	31536895

IC50	6.51		Eur J Med Chem, (2019) 173:None:185	31003060

IC50	6.51		Eur J Med Chem, (2019) 176:None:195	31103900

IC50	6.43		Eur J Med Chem, (2018) 143:None:320	29202397

HDAC3

Tclin

Histone deacetylase 3

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.17		Eur J Med Chem, (2019) 183:None:111691	31536895

HDAC10

Tclin

Histone deacetylase 10

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.11		Eur J Med Chem, (2019) 183:None:111691	31536895