chenodiol
A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.
Ligand Summary
UNII: 0GEI24LG0J
PubChem: 10133
Guide to Pharmacology: 608
ChEMBL: CHEMBL240597
DrugCentral: 4361
LyCHI: T94QFK78ZAN1
Target Activities
NR1H4
Bile acid receptor
2 Activities
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1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
- | 5.3 | |||||
EC50 | 5.47 | AGONIST | ||||
FPR1
fMet-Leu-Phe receptor
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
- | 4 | |||||
GPBAR1
G-protein coupled bile acid receptor 1
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
5.4 | ||||||