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certolizumab pegol

Ligand Summary
Description
A polyethylene-glycolated Fab' fragment of TUMOR NECROSIS FACTOR antibody that binds specifically to TNF-ALPHA and neutralises it in a dose-dependent manner. It also inhibits the production of lipopolysaccharide-induced TNF-ALPHA and IL-1 BETA and is used to treat RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
Synonyms & Links
ChEMBL: CHEMBL1201831
DrugCentral: 4968
LyCHI:  certolizumab pegol


Target Activities