capsaicin
An alkylamide found in CAPSICUM that acts at TRPV CATION CHANNELS.
Ligand Summary
UNII: S07O44R1ZM
PubChem: 1548943
Guide to Pharmacology: 2486
ChEMBL: CHEMBL294199
DrugCentral: 3064
LyCHI: JAL94J53FRK2
Target Activities
TRPV1
Transient receptor potential cation channel subfamily V member 1
21 Activities
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1 – 10 of 21
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
6.1 | ||||||
8 | ||||||
EC50 | 7.5 | |||||
EC50 | 8.6 | Bioorg. Med. Chem., (2010) 18:9:3299 | ||||
EC50 | 8.41 | Bioorg. Med. Chem. Lett., (2012) 22:4:1674 | ||||
EC50 | 8.28 | Bioorg. Med. Chem. Lett., (2015) 25:5:1009 | ||||
Ki | 8.22 | Bioorg. Med. Chem. Lett., (2010) 20:23:7137 | ||||
EC50 | 8.14 | Bioorg Med Chem, (2019) 27:13:2893 | ||||
IC50 | 8.1 | Bioorg. Med. Chem. Lett., (2015) 25:5:1009 | ||||
EC50 | 7.7 | J. Med. Chem., (2002) 45:17:3739 | ||||
KCNA1
Potassium voltage-gated channel subfamily A member 1
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
- | 4.5 | |||||
KCNA2
Potassium voltage-gated channel subfamily A member 2
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 4.4 | |||||
KCNA7
Potassium voltage-gated channel subfamily A member 7
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
4.6 | ||||||
KCNC1
Potassium voltage-gated channel subfamily C member 1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
3.8 | ||||||