caffeine
Ligand Summary
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
UNII: 3G6A5W338E
PubChem: 2519
Guide to Pharmacology: 407
ChEMBL: CHEMBL113
DrugCentral: 463
LyCHI: K2U7RXHYNVYT
Target Activities
7 Activities
Items per page:
10
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