cabozantinib
Ligand Summary
Cabozantinib inhibits the tyrosine kinase activity of MET, VEGFR-1, -2 and -3, AXL, RET, ROS1, TYRO3, MER, KIT, TRKB, FLT-3, and TIE-2. These receptor tyrosine kinases are involved in both normal cellular function and pathologic processes such as oncogenesis, metastasis, tumor angiogenesis, drug resistance, and maintenance of the tumor microenvironment.
UNII: 1C39JW444G
PubChem: 25102847
PubChem: 25102846
Guide to Pharmacology: 5887
ChEMBL: CHEMBL2105717
ChEMBL: CHEMBL2103868
DrugCentral: 4715
LyCHI: LB6JCCMPSY9Z
Target Activities
93 Activities
Items per page:
1 – 10 of 93
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