bremelanotide
Ligand Summary
Bremelanotide is a melanocortin receptor (MCR) agonist that nonselectively activates several receptor subtypes with the following order of potency: MC1R, MC4R, MC3R, MC5R, MC2R. The mechanism by which VYLEESI improves HSDD in women is unknown. The MC1R is expressed on melanocytes; binding at this receptor leads to melanin expression and increased pigmentation
PubChem: 9941379
ChEMBL: CHEMBL2070241
DrugCentral: 5329
LyCHI: V856R6818CCX
Target Activities
3 Activities
Items per page:
10
1 – 3 of 3
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Kd | AGONIST | |||||
Ki | AGONIST | |||||
EC50 | AGONIST | |||||