betrixaban
Ligand Summary
Betrixaban is an oral FXa inhibitor that selectively blocks the active site of FXa and does not require a cofactor (such as Anti-thrombin III) for activity. Betrixaban inhibits free FXa and prothrombinase activity. By directly inhibiting FXa, betrixaban decreases thrombin generation. Betrixaban has no direct effect on platelet aggregation.
UNII: 74RWP7W0J9
PubChem: 10275777
Guide to Pharmacology: 9602
ChEMBL: CHEMBL512351
DrugCentral: 5241
LyCHI: UWAU2T4BDQXG
Target Activities
11 Activities
Items per page:
1 – 10 of 11
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