Pharos: benzbromarone

Target Activities

SLC22A12

Tclin

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1 – 10 of 10

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.66		MedChemComm, (2016) 7:8:1587

IC50	7.58		J. Med. Chem., (2011) 54:8:2701	21449597

IC50	7.46		J. Med. Chem., (2011) 54:8:2701	21449597

IC50	7.46		ACS Med Chem Lett, (2020) 11:10:2017	33062187

IC50	6.92		Bioorg Med Chem Lett, (2017) 27:9:1919	28351592

IC50	6.72		ACS Med Chem Lett, (2020) 11:10:2017	33062187

IC50	6.66		Eur J Med Chem, (2019) 166:None:186	30769179

IC50	6.52		Drug Metab. Dispos., (2007) 35:6:981	17325024

IC50	6.12		None, (2014) None:None:None

IC50	7.59	INHIBITOR	http://www.ncbi.nlm.nih.gov/pubmed/16135657

Tchem

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Tchem

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
Ki	6.72	Bioorg. Med. Chem., (2011) 19:10:3249	21530277

Ki	6.72	https://www.ebi.ac.uk/chembl/compound/inspect/CHEMBL388590

Tchem

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	7.32	J. Med. Chem., (2009) 52:10:3259	19397269

IC50	7.32	https://www.ebi.ac.uk/chembl/compound/inspect/CHEMBL388590