benazepril
prodrug of benazeprilat inhibit angiotensin-converting enzyme (ACE) and results in decreased plasma angiotensin II, which leads to decreased vasopressor activity and to decreased aldosterone secretion
Ligand Summary
UNII: UDM7Q7QWP8
PubChem: 5362124
Guide to Pharmacology: 6374
ChEMBL: CHEMBL838
DrugCentral: 299
LyCHI: ZFAJJB1KUW2L
Target Activities
ACE
Angiotensin-converting enzyme
3 Activities
Items per page:
1 – 3 of 3
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.80000019 | |||||
IC50 | 8.77 | J. Med. Chem., (2000) 43:3:305 | ||||
IC50 | 6.51 | INHIBITOR | ||||