belinostat
a hydroxamate-type inhibitor of histone deacetylase
Ligand Summary
UNII: F4H96P17NZ
PubChem: 6918638
ChEMBL: CHEMBL408513
DrugCentral: 4876
LyCHI: AA7F8LN8G27V
Target Activities
HDAC5
Histone deacetylase 5
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 7.6 | INHIBITOR | ||||
HDAC2
Histone deacetylase 2
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 9.07 | INHIBITOR | ||||
HDAC1
Histone deacetylase 1
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 9.07 | INHIBITOR | ||||
HDAC3
Histone deacetylase 3
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 8.82 | INHIBITOR | ||||
HDAC6
Histone deacetylase 6
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 8.8 | INHIBITOR | ||||
HDAC7
Histone deacetylase 7
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 7.29 | INHIBITOR | ||||
HDAC8
Histone deacetylase 8
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 7.66 | INHIBITOR | ||||
HDAC9
Histone deacetylase 9
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 7.62 | INHIBITOR | ||||
HDAC10
Histone deacetylase 10
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 7.23 | INHIBITOR | ||||
HDAC11
Histone deacetylase 11
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 7.57 | INHIBITOR | ||||
HDAC4
Histone deacetylase 4
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 7.57 | INHIBITOR | ||||
BRD4
Bromodomain-containing protein 4
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 7.57 | |||||