balsalazide
Ligand Summary
a mesalamine 5-aminosalicylate prodrug; 99% of ingested drug remains intact through the stomach and is delivered to and activated in the colon; used for inflammatory bowel disease, ulcerative colitis and radiation-induced proctosigmoiditis but avoided in patients with known hypersensitivity reaction to salicylates or mesalamine
UNII: P80AL8J7ZP
ChEMBL: CHEMBL1201346
DrugCentral: 284
LyCHI: J4Z2ZD967UB2
Target Activities
PTGS2
Prostaglandin G/H synthase 2
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PTGS1
Prostaglandin G/H synthase 1
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ALOX5
Arachidonate 5-lipoxygenase
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PPARG
Peroxisome proliferator-activated receptor gamma
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