androstanolone
Ligand Summary
A potent androgenic metabolite of TESTOSTERONE. It is produced by the action of the enzyme 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE.
UNII: 08J2K08A3Y
PubChem: 10635
Guide to Pharmacology: 2856
ChEMBL: CHEMBL27769
DrugCentral: 3927
LyCHI: FSL18YVLA51P
Target Activities
AR
Androgen receptor
53 Activities
Items per page:
1 – 10 of 53
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 9.3 | |||||
8.65 | ||||||
IC50 | 10.3 | Bioorg. Med. Chem. Lett., (2008) 18:11:3431 | ||||
EC50 | 10.3 | ACS Med. Chem. Lett., (2011) 2:2:124 | ||||
EC50 | 9.89 | J. Med. Chem., (2014) 57:17:7396 | ||||
EC50 | 9.74 | Bioorg. Med. Chem. Lett., (2014) 24:22:5265 | ||||
Ki | 9.7 | J. Med. Chem., (2006) 49:21:6143 | ||||
Ki | 9.7 | Bioorg. Med. Chem. Lett., (2007) 17:6:1523 | ||||
Ki | 9.7 | Bioorg. Med. Chem. Lett., (2007) 17:6:1527 | ||||
Ki | 9.7 | J. Med. Chem., (2007) 50:21:5049 | ||||
SHBG
Sex hormone-binding globulin
3 Activities
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1 – 3 of 3
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 9.74 | J. Med. Chem., (2008) 51:7:2047 | ||||
IC50 | 8.42 | J. Med. Chem., (1990) 33:1:129 | ||||
Kd | 9.74 | |||||
CYP19A1
Aromatase
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.66 | J. Med. Chem., (1989) 32:3:651 | ||||