aminoglutethimide
An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
Ligand Summary
Target Activities
CYP19A1
Aromatase
9 Activities
Items per page:
1 – 9 of 9
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.28 | Bioorg. Med. Chem. Lett., (2010) 20:10:3050 | ||||
IC50 | 6.57 | J. Med. Chem., (2007) 50:12:2799 | ||||
IC50 | 6.57 | J. Med. Chem., (2009) 52:7:1873 | ||||
Ki | 6.33 | J. Med. Chem., (1991) 34:2:725 | ||||
Ki | 6.22 | J. Med. Chem., (1987) 30:9:1550 | ||||
Ki | 6.22 | J. Med. Chem., (1990) 33:11:2933 | ||||
Ki | 6.22 | J. Med. Chem., (1985) 28:2:200 | ||||
Ki | 6.17 | J. Med. Chem., (1986) 29:4:520 | ||||
IC50 | 5.11 | INHIBITOR | ||||
CYP11A1
Cholesterol side-chain cleavage enzyme, mitochondrial
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
INHIBITOR | ||||||