amifampridine
4-Aminopyridine derivative that acts as a POTASSIUM CHANNEL blocker to increase release of ACETYLCHOLINE from nerve terminals. It is used in the treatment of CONGENITAL MYASTHENIC SYNDROMES.
Ligand Summary
UNII: RU4S6E2G0J
PubChem: 5918
ChEMBL: CHEMBL354077
DrugCentral: 4336
LyCHI: TKD5AFJ1327V
Target Activities
KCNQ3
Potassium voltage-gated channel subfamily KQT member 3
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KCNQ2
Potassium voltage-gated channel subfamily KQT member 2
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KCNH1
Potassium voltage-gated channel subfamily H member 1
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KCNA2
Potassium voltage-gated channel subfamily A member 2
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KCNA6
Potassium voltage-gated channel subfamily A member 6
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KCNA3
Potassium voltage-gated channel subfamily A member 3
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KCNA4
Potassium voltage-gated channel subfamily A member 4
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KCNA5
Potassium voltage-gated channel subfamily A member 5
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KCNC1
Potassium voltage-gated channel subfamily C member 1
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KCNQ1
Potassium voltage-gated channel subfamily KQT member 1
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KCNQ4
Potassium voltage-gated channel subfamily KQT member 4
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KCNC4
Potassium voltage-gated channel subfamily C member 4
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KCNA1
Potassium voltage-gated channel subfamily A member 1
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KCNH2
Potassium voltage-gated channel subfamily H member 2
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KCNC3
Potassium voltage-gated channel subfamily C member 3
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KCNB1
Potassium voltage-gated channel subfamily B member 1
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KCNA10
Potassium voltage-gated channel subfamily A member 10
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KCNV1
Potassium voltage-gated channel subfamily V member 1
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KCNH5
Potassium voltage-gated channel subfamily H member 5
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KCNG3
Potassium voltage-gated channel subfamily G member 3
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KCNG4
Potassium voltage-gated channel subfamily G member 4
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KCNV2
Potassium voltage-gated channel subfamily V member 2
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KCNB2
Potassium voltage-gated channel subfamily B member 2
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KCNS1
Potassium voltage-gated channel subfamily S member 1
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KCNH8
Potassium voltage-gated channel subfamily H member 8
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KCNC2
Potassium voltage-gated channel subfamily C member 2
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KCNA7
Potassium voltage-gated channel subfamily A member 7
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KCNS3
Potassium voltage-gated channel subfamily S member 3
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KCNH6
Potassium voltage-gated channel subfamily H member 6
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KCNF1
Potassium voltage-gated channel subfamily F member 1
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KCNQ5
Potassium voltage-gated channel subfamily KQT member 5
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