aflibercept
Ligand Summary
has antiangiogenic activity; consists of the second and third Ig domains of VEGFR1 and VEGFR2, respectively, fusion to the Fc region of IgG1; putative antineoplastic agent that binds all VEGF-A isoforms; possible medicine for eye disorders
ChEMBL: CHEMBL1742982
DrugCentral: 4916
LyCHI: aflibercept
Target Activities
3 Activities
Items per page:
10
1 – 3 of 3
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | INHIBITOR | |||||
Kd | INHIBITOR | |||||
Kd | INHIBITOR | |||||