adenosine triphosphate
An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Ligand Summary
UNII: 8L70Q75FXE
PubChem: 5957
Guide to Pharmacology: 1713
ChEMBL: CHEMBL14249
DrugCentral: 91
LyCHI: 13MPPKL52AL3
Target Activities
P2RY2
P2Y purinoceptor 2
6 Activities
Items per page:
1 – 6 of 6
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 7.52 | J. Med. Chem., (2009) 52:9:2762 | ||||
EC50 | 7.2 | J. Med. Chem., (2009) 52:9:2762 | ||||
EC50 | 7.07 | J. Med. Chem., (2002) 45:10:2090 | ||||
EC50 | 7.07 | J. Med. Chem., (2007) 50:6:1166 | ||||
EC50 | 7.07 | Bioorg. Med. Chem. Lett., (2009) 19:11:3002 | ||||
EC50 | 7.02 | J. Med. Chem., (2009) 52:9:2762 | ||||
P2RX4
P2X purinoceptor 4
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 6 | |||||
EC50 | 6.3 | |||||
EC50 | 6.3 | J. Med. Chem., (2002) 45:19:4057 | ||||
EC50 | 6 | J. Med. Chem., (2012) 55:22:9576 | ||||
EC50 | 6.3 | AGONIST | ||||
TRPM4
Transient receptor potential cation channel subfamily M member 4
4 Activities
Items per page:
1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
5.8 | ||||||
6.1 | ||||||
4.9 | ||||||
IC50 | 5.8 | BLOCKER | ||||
P2RX1
P2X purinoceptor 1
3 Activities
Items per page:
1 – 3 of 3
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 7.25 | |||||
EC50 | 7.25 | J. Med. Chem., (2002) 45:19:4057 | ||||
EC50 | 7.25 | AGONIST | ||||
GPR17
Uracil nucleotide/cysteinyl leukotriene receptor
2 Activities
Items per page:
1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 7.43 | |||||
EC50 | 7.43 | AGONIST | ||||
P2RX3
P2X purinoceptor 3
2 Activities
P2RY4
P2Y purinoceptor 4
2 Activities
P2RX2
P2X purinoceptor 2
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 5.85 | |||||
P2RX5
P2X purinoceptor 5
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 6 | |||||
P2RX6
P2X purinoceptor 6
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 6 | |||||
P2RX7
P2X purinoceptor 7
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 3.11 | |||||
P2RY13
P2Y purinoceptor 13
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
5.4 | ||||||
P2RY1
P2Y purinoceptor 1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
4.8 | ||||||