adenosine
A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.
Ligand Summary
UNII: K72T3FS567
PubChem: 60961
Guide to Pharmacology: 2844
ChEMBL: CHEMBL477
DrugCentral: 90
LyCHI: QVB8Q7NQV6B5
Target Activities
ADORA2A
Adenosine receptor A2a
4 Activities
ADORA1
Adenosine receptor A1
4 Activities
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1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.63 | J. Med. Chem., (2016) 59:3:947 | ||||
Ki | 7.14 | |||||
Ki | 7 | |||||
EC50 | 6.5086 | AGONIST | ||||
ADORA3
Adenosine receptor A3
3 Activities
ADORA2B
Adenosine receptor A2b
3 Activities
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1 – 3 of 3
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 4.82 | |||||
Ki | 5.29 | |||||
EC50 | 4.6198 | AGONIST | ||||
TRPM4
Transient receptor potential cation channel subfamily M member 4
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 3.20000005 | |||||