abciximab
Ligand Summary
A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX, potently inhibiting PLATELET AGGREGATION. It is used in treatment of refractory unstable angina, and for prevention of ischemic complications in patients undergoing percutaneous coronary procedures such as ANGIOPLASTY; ATHERECTOMY; or stenting.
ChEMBL: CHEMBL1201584
DrugCentral: 4950
LyCHI: abciximab
Target Activities
2 Activities
Items per page:
10
1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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ANTIBODY BINDING | ||||||
ANTIBODY BINDING | ||||||