You are using an outdated browser. Please upgrade your browser to improve your experience.


Ligand Summary
A fusion protein immunoconjugate of the extracellular domain of CTLA4 and the Fc domain of human IgG1. It functions as a T-cell co-stimulation blocker that inhibits TNF-ALPHA and prevents the activation of T-LYMPHOCYTES. It is used in the treatment of RHEUMATOID ARTHRITIS.
Synonyms & Links
DrugCentral: 5089
LyCHI:  abatacept

Target Activities