CHEMBL3326006
Ligand Summary
Name: trans-4-(2-(Butylamino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexan-1-ol
ChEMBL: CHEMBL3326006
LyCHI: ZZ22JYZUUL3Z
Target Activities
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10
1 – 10 of 10
MERTK
Tyrosine-protein kinase Mer
3 Activities
FLT3
Receptor-type tyrosine-protein kinase FLT3
2 Activities
AXL
Tyrosine-protein kinase receptor UFO
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.85 | J. Med. Chem., (2014) 57:16:7031 | ||||
NUAK1
NUAK family SNF1-like kinase 1
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.1 | J. Med. Chem., (2014) 57:16:7031 | ||||
NTRK1
High affinity nerve growth factor receptor
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.78 | J. Med. Chem., (2014) 57:16:7031 | ||||
SIK2
Serine/threonine-protein kinase SIK2
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.24 | J. Med. Chem., (2014) 57:16:7031 | ||||
TYRO3
Tyrosine-protein kinase receptor TYRO3
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.77 | J. Med. Chem., (2014) 57:16:7031 | ||||
SLK
STE20-like serine/threonine-protein kinase
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.21 | J. Med. Chem., (2014) 57:16:7031 | ||||
KIT
Mast/stem cell growth factor receptor Kit
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.09 | J. Med. Chem., (2014) 57:16:7031 | ||||
NTRK3
NT-3 growth factor receptor
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.36 | J. Med. Chem., (2014) 57:16:7031 | ||||