isofagomine
Ligand Summary
Name: isofagomine
PubChem: 447607
PubChem: 70697642
ChEMBL: CHEMBL206468
ChEMBL: CHEMBL2105671
LyCHI: ZM4Z6CGUGJXQ
Target Activities
GBA
Glucosylceramidase
9 Activities
Items per page:
1 – 9 of 9
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.72 | J. Med. Chem., (2012) 55:12:5734 | ||||
IC50 | 7.52 | J. Med. Chem., (2012) 55:12:5734 | ||||
IC50 | 7.52 | J. Med. Chem., (2012) 55:12:5734 | ||||
IC50 | 7.23 | Nat. Chem. Biol., (2007) 3:2:101 | ||||
IC50 | 7.22 | Bioorg. Med. Chem., (2008) 16:15:7330 | ||||
IC50 | 7.2 | Bioorg. Med. Chem., (2011) 19:11:3558 | ||||
IC50 | 7.1 | MedChemComm, (2012) 3:1:56 | ||||
Ki | 6.66 | MedChemComm, (2016) 7:2:365 | ||||
IC50 | 6.13 | MedChemComm, (2016) 7:2:365 | ||||
PYGL
Glycogen phosphorylase, liver form
2 Activities
GBA2
Non-lysosomal glucosylceramidase
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.7 | Bioorg Med Chem, (2018) 26:20:5462 | ||||