Pharos : Ligand Details - ZM4Z6CGUGJXQ

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Ligand Summary

Ligand Structure

chemical structure image

Synonyms & Links

Name: Isofagomine

PubChem: 447607

PubChem: 70697642

ChEMBL: CHEMBL206468

ChEMBL: CHEMBL2105671

LyCHI: ZM4Z6CGUGJXQ

Target Activities

Items per page:

10

1 – 2 of 2

GBA

Tclin

Glucosylceramidase

6 Activities

Items per page:

1 – 6 of 6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.13		MedChemComm, (2016) 7:2:365

Ki	6.66		MedChemComm, (2016) 7:2:365

IC50	7.2		Bioorg. Med. Chem., (2011) 19:11:3558	21546253

IC50	7.22		Bioorg. Med. Chem., (2008) 16:15:7330	18595718

IC50	7.23		Nat. Chem. Biol., (2007) 3:2:101	17187079

IC50	7.52		J. Med. Chem., (2012) 55:12:5734	22646221

PYGL

Tchem

Glycogen phosphorylase, liver form

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.16		Bioorg. Med. Chem., (2008) 16:15:7330	18595718

IC50	6.17		J. Med. Chem., (2006) 49:19:5687	16970395