Pharos : Ligand Details

Target Activities

Explore Associated and Predicted Targets

BRD4

Tchem

Bromodomain-containing protein 4

5 Activities

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1 – 5 of 5

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
Kd	7.38	J Med Chem, (2020) 63:6:3227	32091206

IC50	7.08	Science Advances, (2016) None:10:e1600760	27757418

IC50	6.93	Science Advances, (2016) None:10:e1600760	27757418

IC50	6.51	Science Advances, (2016) None:10:e1600760	27757418

IC50	6.33	Science Advances, (2016) None:10:e1600760	27757418

CECR2

Tchem

Cat eye syndrome critical region protein 2

5 Activities

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1 – 5 of 5

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
Kd	8.1	Science Advances, (2016) None:10:e1600760	27757418

IC50	8.03	Science Advances, (2016) None:10:e1600760	27757418

Kd	8	J Med Chem, (2020) 63:10:5212	32321240

IC50	7.32	Science Advances, (2016) None:10:e1600760	27757418

IC50	7.1	Science Advances, (2016) None:10:e1600760	27757418

BRD9

Tchem

Bromodomain-containing protein 9

5 Activities

Items per page:

1 – 5 of 5

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	7.33	Science Advances, (2016) None:10:e1600760	27757418

Kd	6.94	J Med Chem, (2020) 63:6:3227	32091206

IC50	6.8	Bioorg Med Chem, (2019) 27:7:1391	30824168

IC50	6.52	Science Advances, (2016) None:10:e1600760	27757418

IC50	6.15	Science Advances, (2016) None:10:e1600760	27757418

BRDT

Tchem

Bromodomain testis-specific protein

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
Kd	7.4	Science Advances, (2016) None:10:e1600760	27757418

Kd	6.76	Science Advances, (2016) None:10:e1600760	27757418

BRD2

Tchem

Bromodomain-containing protein 2

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.3		Science Advances, (2016) None:10:e1600760	27757418

BRD7

Tchem

Bromodomain-containing protein 7

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	6.41		J Med Chem, (2020) 63:6:3227	32091206

BRPF1

Tchem

Peregrin

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.85		Science Advances, (2016) None:10:e1600760	27757418

TAF1

Tchem

Transcription initiation factor TFIID subunit 1

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.78		Science Advances, (2016) None:10:e1600760	27757418